Melasma is a type of skin hyperpigmentation characterized by brown-grayish patches with irregular borders, symmetrically distributed mostly on the face. It mainly affects women of childbearing age and is linked to a mix of hormonal factors, sun exposure, and genetic predisposition. It shows up as visible and persistent discolorations that disrupt the skin's even tone and tend to come back.
is an advanced clinical-cosmetic approach that combines specific technologies, personalized protocols, and prevention strategies to tackle the root causes of hyperpigmentation, reduce spots and discolorations, and restore skin’s radiance.
In institute
The Melas treatment gradually retrains hyperpigmented skin through a series of precise stimulations that regulate inflammatory and melanogenic processes responsible for discolorations, selectively targeting the key points of pigment dysfunction without irritating or sensitizing the skin.
Treatment duration
70 minutes
Active ingredients in the cabin with effective concentrations
15% Phytic Acid, 5% Azamide, 0.4% Luminyl
Visible results immediately and over time
Smoother, more even skin, free from spots and discolorations
Skin Recovery
Included in the protocol is a recovery cream for home use, to be applied during the first 48 hours post-treatment to support the skin’s regenerative phase
Multi-level action on the key drivers of melasma.
Action in the corneocyte
Selective and accelerated depigmentation of hyperpigmented areas.
Action in the melanosome
Regulation of communication between the skin layers and targeted slowing down of new melanin synthesis.
Action on the melanocyte
Neuro-cutaneous modulation of inflammatory signals underlying pigment activation.
homecare
The Melas home phase ensures the continuation of biological signals triggered in the treatment cabin, to prevent the reappearance of spots and promote a stable and long-lasting normalization of pigmentation over time.
Depigmenting facial emulsion - 50 ml
2% Tranexamic Acid
Daily day and night emulsion that visibly reduces discolorations and prevents their formation on skin prone to hyperpigmentation: selectively blocks excess melanin, regulates inflammation without disrupting skin balance, renews the skin, and evens out the tone.
SIZE
50 ml
TEXTURE
Emulsion
HOW TO USE
Apply morning and evening with gentle movements on the face, neck, and décolleté
INGREDIENTS (INCI)
AQUA/WATER/EAU, DICAPRYLYL ETHER, GLYCERIN, CAPRYLIC/CAPRIC TRIGLYCERIDE, CAMELLIA JAPONICA SEED OIL, ADANSONIA DIGITATA SEED OIL, TRANEXAMIC ACID, PROPANEDIOL, CALCIUM ALUMINUM BOROSILICATE, PHENOXYETHANOL, POLYACRYLATE-13, POLYGLYCERYL-3 COCOATE, LECITHIN, POLYISOBUTENE, HYDROGENATED LECITHIN, INULIN LAURYL CARBAMATE, TOCOPHEROL, ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER, XANTHAN GUM, HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL, CAPRYLYL GLYCOL, DISODIUM EDTA, POLYSORBATE 20, SODIUM HYDROXIDE, SORBITAN ISOSTEARATE
Nighttime Depigmenting Face Treatment - 30 ml
2.5% Phytic Acid
The intensive treatment that brightens hyperpigmented skin: prevents and counteracts the formation of spots for an intensive overnight evening effect. Depigmenting and skin tone evening, it reduces post-inflammatory discolorations and regenerates the skin in a controlled and gradual way.
SIZE
30 ml
TEXTURE
Fluid hydrogel
HOW TO USE
Apply in the evening with gentle pressing on the face, neck, and décolleté, after the emulsion.
INGREDIENTS (INCI)
AQUA/WATER/EAU, PENTYLENE GLYCOL, PROPYLENE GLYCOL, PHYTIC ACID, CALCIUM ALUMINUM BOROSILICATE, SODIUM POLYACRYLOYLDIMETHYL TAURATE, SODIUM HYDROXIDE, LEVULINIC ACID
vegan
ok
made in
Italy
clinical tests
under dermatological
control
effectiveness
backed up
by clinical tests
fragrance
free
90%
The skin looks fresher and more vibrant.*
70%
The pigmentation of spots is less intense.*
70%
The outline of the spots appears less sharp and defined.*
85%
The face looks more even-toned even without makeup: the color correction is noticeable.*
70%
There’s a sense that the treatment has a preventive effect against the formation of new discolorations.*
More than half of the respondents noticed a reduction in the visibility of stubborn spots, those they’d been itching to get rid of for years.*
90%
It feels like the products work both on the skin’s surface and deep down.*
*Clinical tests conducted under Dermatological supervision on a panel of 20 women aged 40 to 65, at a certified Laboratory; combined use of MELANOGENIX CREAM + MELANOGENIX TREATMENT for 28 days.
Now you can see the effects
LEGEND
Images with and without filters acquired and processed using Skin Test EVO investigation technology. Subjects underwent professional treatments and used both Research home-use products.
Clinical tests carried out under Dermatological supervision on a panel of 100 women, at a certified Laboratory; combined use of both home-use products for 28 days.
FAQ
Will the spots on my face go away?
The treatment is designed to progressively reduce discolorations. The goal isn’t just to visually tone them down but also to regulate the underlying processes that cause them: overproduction of melanin, inflammation, and oxidative stress. Results are gradual and lasting—not instant or temporary.
Are there any contraindications?
The Melas treatment isn’t recommended during pregnancy, breastfeeding, ongoing dermatological therapies, or on skin that is highly irritated or sensitized by recent treatments. Each case is assessed individually during the consultation.
I’m worried it might be too harsh for my skin.
The Melas protocol uses peels and depigmenting actives at safe concentrations, applied in a controlled sequence. The action is gradual and targeted, aiming for results without causing damage or lasting irritation.
When will I see the first results?
The timing varies depending on the type and depth of the spots. In some cases, the skin looks brighter right after the first session; in others, improvements become noticeable progressively in the following treatments.
How long will the results last?
The protocol targets the root causes of discoloration, not just the surface appearance, promoting long-lasting results. However, it largely depends on consistent use of home treatments, sun protection, and how well the maintenance program is managed over the following months: without these precautions, spots tend to come back.
Is it a medical treatment?
No, melas is an advanced aesthetic treatment based on clinically-inspired dermatological protocols. It doesn’t require medical supervision but leverages up-to-date scientific knowledge to maximize safety and effectiveness.
Are there any risks?
The protocol is completely safe. During the process, you might temporarily experience mild darkening of the spots, redness, or peeling, which are normal physiological reactions of skin undergoing activation.
Can I expose myself to the sun right after the treatment?
No, sun exposure should be avoided. Skin treated for hyperpigmentation remains more sensitive to light stimuli, and sun radiation is one of the main triggers that fuel and reactivate spots. That’s why daily protection and minimizing direct exposure not only for 48 hours after treatment but throughout the entire course and beyond is essential.
Is the treatment painful?
No, it’s not painful; however, some phases may cause tingling, warmth, or slight skin tension: these are controlled, temporary effects linked to the physiological activation of the renewal processes.
What should I expect after the session?
You might notice slight peeling or a temporary darkening of pigmented areas: these are normal physiological responses indicating the protocol is working properly.
Can I stop the treatment if I see reactions?
No, do not stop the treatment on your own. Any reactions will be assessed by the Dermotechnologist and are expected skin responses. Stopping the treatment risks compromising the entire process.
How many sessions are needed?
The full MELAS protocol involves 5 consecutive sessions, one per week.
Can I undergo the treatment if I'm taking medications?
Some medications (like photosensitizers, hormones…) can affect skin pigmentation or sensitivity. It's crucial to always disclose this during your medical history and throughout the treatment, so any necessary adjustments can be made.
What happens if I miss a session?
The MELAS protocol requires weekly sessions to ensure continuity and effectiveness. Any delay should be made up as soon as possible to keep the sequence of treatments uninterrupted.
Is it suitable during the summer?
No, the protocol is not recommended during periods of sun exposure. If unavoidable circumstances require you to undergo treatment in summer, it’s absolutely essential to follow the Dermotechnologist's instructions carefully, who will prescribe specific home care products and special protective measures to minimize the risk of spots returning or worsening.
Can I combine it with other aesthetic treatments?
It’s best not to overload your skin with other treatments during the protocol to avoid interference and maintain stable results. Any combination must be evaluated by the Dermotechnologist.
How long should I wait after the treatment before waxing or facial hair removal?
It’s recommended to wait at least 48 hours after the session before waxing or performing any facial hair removal.
I’ve had an aesthetic medicine treatment (botox, fillers, laser, needling, etc.): can I undergo this treatment?
It depends on the type of treatment and how much time has passed. In any case, your skin’s condition will be assessed and the most suitable protocol will be proposed, considering methods and timing.
Can I continue with my usual at-home beauty routine?
The protocol includes a specific home program with Melanogenix products. Using other non-prescribed products may reduce or compromise the results, or negatively interact with the active ingredients in the protocol.
Can I put on makeup after the treatment?
Yes, after the treatment you can apply your usual makeup, preferably choosing formulations that are tested and compatible with sensitive skin prone to discoloration.
